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PPI-GIT1/β-Pix interaction-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-152095
    PPI-GIT1/β-Pix interaction-IN-1

    		Ras Cancer
    PPI-GIT1/β-Pix interaction-IN-1 is a potent and orally active GIT1/β-Pix protein-protein interaction (PPI) inhibitor with a KD value of 7.7 µM. PPI-GIT1/β-Pix interaction-IN-1 disrupts the GIT/PIX interaction can impact the activation of the downstream Rho GTPase Rac1 and Cdc42. PPI-GIT1/β-Pix interaction-IN-1 inhibits metastasis of gastric cancer .
    <em>PPI-GIT1</em>/<em>β-Pix</em> <em>interaction-IN-1</em>

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